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Illumina, Inc.

ILMN ·Technology, Scientific & Technical Instruments, United States
Analysis › KPI Dashboard

As of Fiscal Year 2025 (ended December 28, 2025)

Key KPIs at a Glance

Metric Value
Total Revenue (FY2025) $4,343 million
Net Income, GAAP (FY2025) $850 million
GAAP Operating Margin (FY2025) 18.6%
Non-GAAP Operating Margin (FY2025) 23.1%
Consumables Revenue (FY2025, est.) ~$3,214 million (74% of total revenue)
NovaSeq X Installed Base (as of Q4 2025) ~890 instruments (100+ placed in Q4 2025 alone)
Full-Time Employees (as of Dec 28, 2025) ~8,600

Revenue by Product Category (FY2025)

Total Revenue: $4.34B

Illumina's consolidated FY2025 revenue of $4,343M by product category, calculated by applying the percentages disclosed in the FY2025 Form 10-K (Consumables 74%, Instruments 11%, Services and Other 15%) to total revenue; dollar figures are therefore approximate. FY2025 is fully post-GRAIL (GRAIL spun off June 24, 2024), so this breakdown reflects continuing operations only.

Total Revenue Growth

Core Illumina revenue (continuing operations, excluding GRAIL) for FY2021-FY2024, and consolidated FY2025 revenue (GRAIL fully divested as of June 24, 2024, so no adjustment is needed for FY2025). Source: Illumina's FY2022, FY2024 and FY2025 Q4/full-year earnings releases, which separately disclose 'Core Illumina' revenue ex-GRAIL.

Sources: Illumina divested GRAIL via spin-off completed June 24, 2024. Per Illumina's FY2025 Form 10-K, the GRAIL disposition did not meet accounting criteria for discontinued-operations treatment, so GRAIL's results remain embedded in Illumina's consolidated GAAP financials for FY2021-FY2024, including large GRAIL-related goodwill/IPR&D impairments that drove consolidated GAAP net losses of $(4.404) billion in FY2022 and $(1.223) billion in FY2024. To present a consistent continuing-operations view, the revenue-history chart uses Illumina's self-reported 'Core Illumina' (ex-GRAIL) revenue for FY2021-FY2024 and consolidated FY2025 revenue (no GRAIL remains post-divestiture, so FY2025 consolidated = Core Illumina). All other FY2025 figures (revenue mix, net income, margins, KPIs) are Illumina's reported continuing-operations results, which are not affected by GRAIL. Sources: Illumina Q4 & Fiscal Year 2025 Earnings Release (Feb 5, 2026); Illumina FY2025 Form 10-K (fiscal year ended Dec 28, 2025); Illumina Q4 & Fiscal Year 2024 Earnings Release (Feb 2025); Illumina Q4 & Fiscal Year 2022 Earnings Release (Feb 2023); Illumina Q4 2025 earnings call transcript (Feb 5, 2026).