SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person* TCG Crossover GP II, LLC (Last) (First) (Middle) 245 LYTTON AVE., SUITE 350 (Street) PALO ALTO CALIFORNIA 94301 (City) (State) (Zip) UNITED STATES (Country)	2. Date of Event Requiring Statement (Month/Day/Year) 03/30/2026	3. Issuer Name and Ticker or Trading Symbol Vor Biopharma Inc. [ VOR ]
		3a. Foreign Trading Symbol	5. If Amendment, Date of Original Filed (Month/Day/Year)
		4. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director X 10% Owner Officer (give title below) Other (specify below)	6. Individual or Joint/Group Filing (Check Applicable Line) Form filed by One Reporting Person X Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock	2,836,539	I	See footnote(1)
Common Stock	2,836,539	I	See footnote(2)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

1. Name and Address of Reporting Person* TCG Crossover GP II, LLC (Last) (First) (Middle) 245 LYTTON AVE., SUITE 350 (Street) PALO ALTO CALIFORNIA 94301 (City) (State) (Zip) UNITED STATES (Country) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* TCG Crossover Fund II, L.P. (Last) (First) (Middle) 245 LYTTON AVE., SUITE 350 (Street) PALO ALTO CALIFORNIA 94301 (City) (State) (Zip) UNITED STATES (Country) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* TCG Crossover GP III, LLC (Last) (First) (Middle) 245 LYTTON AVE., SUITE 350 (Street) PALO ALTO CALIFORNIA 94301 (City) (State) (Zip) UNITED STATES (Country) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* TCG Crossover Fund III, L.P. (Last) (First) (Middle) 245 LYTTON AVE., SUITE 350 (Street) PALO ALTO CALIFORNIA 94301 (City) (State) (Zip) UNITED STATES (Country) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

Explanation of Responses:

1. These securities are held of record by TCG Crossover Fund II, L.P. (TCG Crossover II). TCG Crossover GP II, LLC (TCG Crossover GP II) is the general partner of TCG Crossover II and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP II and may be deemed to share voting, investment and dispositive power with respect to these securities.

2. These securities are held of record by TCG Crossover Fund III, L.P. (TCG Crossover III). TCG Crossover GP III, LLC (TCG Crossover GP III) is the general partner of TCG Crossover III and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP III and may be deemed to share voting, investment and dispositive power with respect to these securities.

	/s/ TCG Crossover GP II, LLC /s/ Craig Skaling, Authorized Signatory	04/01/2026
	/s/ TCG Crossover Fund II, L.P. /s/ Craig Skaling, Authorized Signatory	04/01/2026
	/s/ TCG Crossover GP III, LLC /s/ Craig Skaling, Authorized Signatory	04/01/2026
	/s/ TCG Crossover Fund III, L.P. /s/ Craig Skaling, Authorized Signatory	04/01/2026
	/s/ Craig Skaling, as Attorney-in-Fact for Chen Yu	04/01/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 3: SEC 1473 (03-26)