Alnylam Pharmaceuticals, Inc.

ALNY ·Healthcare, Drug Manufacturers - General, United States
Financial Statements › Income Statement
Annual Quarterly

Income Statement

Line Item FY2025 FY2024 FY2023 FY2022 FY2021 FY2020 FY2019 FY2018
Revenue $3.71B $2.25B $1.83B $1.04B $844.3M $492.9M $219.8M $74.9M
ONPATTRO $172.8M $252.9M $354.5M $557.6M $474.7M $306.1M — —
AMVUTTRA $2.31B $970.5M $557.8M $93.8M $0 $0 — —
GIVLAARI $308.5M $255.9M $219.3M $173.1M $127.8M $55.1M — —
OXLUMO $191.4M $167.1M $109.8M $69.8M $59.6M $333.0K — —
Collaboration and other revenue $553.4M $510.2M $546.2M $134.9M $181.0M $131.3M — —
Royalty revenue $174.0M $91.8M $40.6M $8.2M $1.2M $0 — —
Cost of Revenue $677.2M $306.5M $268.2M $140.2M $115.0M $74.2M $25.1M $1.8M
Gross Profit $3.04B $1.94B $1.56B $897.2M $729.3M $418.7M $194.7M $73.1M
Gross Margin 81.8% 86.4% 85.3% 86.5% 86.4% 84.9% 88.6% 97.6%
Operating Expenses
Research & Development $1.32B $1.13B $1.00B $883.0M $792.2M $654.8M $655.1M $505.4M
SG&A Expense $1.21B $975.5M $795.6M $770.7M $620.6M $588.4M $479.0M $382.4M
Operating Income $501.6M $-176.9M $-282.2M $-785.1M $-708.7M $-828.4M $-939.4M $-814.7M
Operating Margin 13.5% -7.9% -15.4% -75.7% -83.9% -168.1% -427.5% -1,087.6%
Interest Expense — — $121.2M $156.0M $143.0M $84.5M $0 $0
Pretax Income $323.2M $-377.4M $-433.5M $-1.13B $-852.1M $-855.6M $-885.3M $-760.7M
Income Tax Expense $9.4M $-99.2M $6.7M $4.2M $680.0K $2.7M $863.0K $823.0K
Net Income $313.7M $-278.2M $-440.2M $-1.13B $-852.8M $-858.3M $-886.1M $-761.5M
Net Margin 8.4% -12.4% -24.1% -109.0% -101.0% -174.1% -403.2% -1,016.6%
EPS (Basic) $2.39 $-2.18 $-3.52 $-9.30 $-7.20 $-7.46 $-8.11 $-7.57
EPS (Diluted) $2.33 $-2.18 $-3.52 $-9.30 $-7.20 $-7.46 $-8.11 $-7.57
Shares Outstanding (Basic) 131.0M 127.7M 124.9M 121.7M 118.5M 115.0M 109.3M 101.2M
Shares Outstanding (Diluted) 134.7M 127.7M 124.9M 121.7M 118.5M 115.0M 109.3M 101.2M
Dividends Per Share — — — — — — — —
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